Mahakalyanaka Ghritam Saptavarthi

Mahakalyanaka Ghritam Saptavarthi is an effective Ayurvedic Medicine for Neuronal Degenerative diseases like Alzheimer’s, Huntington’s, Parkinson’s, Dementia, Cognitive disorders, Epilepsy, and Female Infertility.

Mahakalyanaka GhritamActions of Mahakalyanaka Ghritam Saptavarthi:
      • Anxiolytic action of Valeric Acid of Mahakalyanaka ghritam reduces Serotonin and Norepinephrine in Hippocampus.
      • Aqueous Valerian extracts show significant Anti- Convulsant activity.
      • Levodopa and 5-HT play an important role in Anticataleptic and Antiepileptic function.
      • Reduces accumulation of Amyloid-β (Aβ) plaques, the major cause of Alzheimer’s disease.
      • Enhances levels of serotonin, Dopamine & Gamma-aminobutyric acid and thus is effective in Autism Spectrum diseases.
      • Inhibits acetylcholinesterase activity, reduces lipid peroxidation in the brain, facilitates dissociation of Aβ oligomers, and protects against Aβ-induced apoptosis.
      • Punicalagin (PNCG) and Ellagic acid (EA) have Antidepressant and Anxiolytic actions which reduce immobility, increase Brain Serotonin levels, and also reduce oxidative stress in the Brain.
      • Sterols, and Triterpenoids in Mahakalyanaka ghritam exhibit significant learning and memory activity, modulate oxidative stress and exert a protective effect against oxidative damage to Neurons.
      • Stigmasterol of Mahakalyanaka ghritam is the precursor of progesterone, acts as an intermediate in the biosynthesis of estrogen and corticoids, and normalizes Ovulation.
      • Sterols in Ghee enhance the synthesis of steroid hormones i.e., estrogen and progesterone.
      • Scavenges radicles and suppresses the pathways by protecting against further neurological damage due to oxidative or nitrosative stress sources in the brain, this results in remission of depression or anxiety symptoms.
      • The medicaments in ghee form rapidly get absorbs into the bloodstream and reach target areas of the Central Nervous system faster.
      • This formulation acts in normalizing the chemical changes in the brain by balancing the neuro-transmitters responsible for the mental disorders.

Caution: Above content is for information only, not for self-treatment or diagnosis. Medications are to be strictly taken under Ayurvedic physician’s prescription only.

Ref: Ashtanga Hridayam,  Uttarasthana,  Adhyayam  6

Composition: Each 300 mg soft gelatin capsule contains medicaments prepared out of

Sanskrit Name Scientific Name Part Used Qty.
Kshiram Cow’s milk 9.24 ml
Amalaki Emblica officinalis Fr 0.131 g
Haritaki Terminalia chebula Fr 0.131 g
Vibhitaki Terminalia bellerica Fr 0.131 g
Bhadra Ela Amomum subulatum Fr 0.131 g
Devadaru Cedrus deodara Ht Wd 0.131 g
Valuka Radermachera xylocarpata Rt 0.131 g
Sariba Hemidesmus indicus Rt 0.131 g
Krishnasariba Ichnocarpus frutescens Rt 0.131 g
Haridra Curcuma longa Rz 0.131 g
Daruharidra Berberis aristata St Bk 0.131 g
Salaparni Desmodium gangeticum Pl 0.131 g
Prisniparni Uraria picta Pl 0.131 g
Priyangu Callicarpa macrophylla Fl 0.131 g
Tagara Valeriana walichii Rz 0.131 g
Brihati Solanum indicum Pl 0.131 g
Kushtha Saussurea lappa Rt 0.131 g
Manjishta Rubia cordifolia St 0.131 g
Nagakesara Mesua ferrea Fl 0.131 g
Dadima Punica granatum Sd 0.131 g
Vidanga Embelia ribes Sd 0.131 g
Talisapatra Abies webbiana Lf 0.131 g
Ela Elettaria cardamomum Fr 0.131 g
Malathimukula Jasminum grandiflorum Fl 0.131 g
Utpala Kaempferia rotunda St 0.131 g
Danti Baliospermum montanum Rt 0.131 g
Padmaka Prunus cerasoides St 0.131 g
Chandana Santalum album Ht Wd 0.131 g
Varuni Coccinia grandis Fr 0.024 g
Riddhi Curculigo orchioides (sub.) Rt 0.024 g
Meda Asparagus racemosus (sub.) Rt 0.024 g
Kakoli Withania somnifera (sub.) Rt 0.024 g
Kapikachu Mucuna pruriens Sd 0.024 g
Vishani Gymnema sylvestre Lf 0.024g
Mashaparni Teramnus labialis Pl 0.024g
Mudgaparni Phaseolus trilobus Pl 0.024g
Ghritam Cow Ghee 300 mg

Dosage: 1 capsule twice or thrice a day or as advised by Vaidya.
Anupana:Warm milk or Warm water.
Indications: Manovikara, Apasmara, Pandu, Chittodvega, Vandhyatva.
Presentation: 10×10 Capsules Blister pack, 1000s Jar.



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