OJOPLUS Tablets

For Immune Boosting and Management of Viral Infections

Government Of India AYUSH department SUGGESTED formula of TULASI, SUNTHI , MARICHA, DALCHINI for Immune Boosting in wake of COVID 19 Pandemic

OJOPLUS is fortified with additional ingredients with Proven Immunomodulatory, Anti Airway Inflammatory activity and preventing Disseminated Intra vascular Coagulation

This is a major improvement over the, AYUSH formula and will have better efficacy.

1.Boost Both Innate and Adaptive Immunity
2. Reduce the Airway Inflammation,
3. AntiPyretic activity
4.Minimise Intra vascular coagulation

OJOPLUS TABLET is Add on supplementary Therapy with Specific Therapeutic targets to Boost Immunity, Improve the Clinical Outcome In Viral infections, Reduce the Severity of Complication,

Immunomodulation activity

Haridra Curcuma longa: Curcumin effectively modulates the function of T cells, B cells, Monocytes, Macrophages (mφ) and Neutrophils. Increases number of activated CD4+ T cells, & enhanced level of B cells, activation of Natural Killer cells

Tulasi Ocimum sanctum: Eugenol, Ursolic acid Modulates humoral responses in the immune system such as Antibody production and has stimulatory effect on T & B lymphocytes by enhancement in IL-2 production.

Guduchi Tinospora cordifolia: Extract significantly increased in the Serum immunoglobulin levels , Total leucocyte count, Absolute lymphocyte count (ALC) and Lymphocyte percentage. Activates macrophages.

Aswagandha Withania somnifera:Withanaloids enhances circulating Antibody titre, total WBC count and enhancement in Phagocytic activity of Peritoneal macrophages

Limiting Airway inflammation.

Curcuma longa:Curcumin significantly inhibited Myofibroblast activation, limiting the pathogenesis of Viral-induced ARDS,decreases the inflammatory cells infiltration in the lung tissues and Bronchoalveolar Lavage Fluid .

Glycirrhiza glabra : Glycirrhizin reduced IL-8 generation in Lung fibroblasts and inhibits Eotaxin 1 reducing Eosinophils infiltration into the airways after Inflammatory stimulation.

Tulasi Ocimum sanctum:Eugenol exerts Bronchial smooth muscle relaxation. Ursolic acid in the volatile oil may be responsible for anti-inflammatory activity, Via inhibition of COX .

Sunthi Zingiber officinale : Gingerol reduces Inflammatory response by reducing Immunoglobulin E thereby relieving Respiratory distress

Dalchini Cinnamomum zeylanicum : Cinnamaldehyde has Antimicrobial and Anti Inflammatory actions

Maricha Piper nigrum: Piperine suppressed the inflammatory cells accumulation, specifically with eosinophils in Nasal Tissue .

Antipyretic activity

Tinospora cordifolia: Aqueous extract of T. cordifolia produced dose dependent highly significant reduction in temperature. The temperature returned to normal in 2hrs. This effect was similar to that of standard drug paracetamol.

Minimising Disseminated intravascular coagulation (DIC)

Curcuma longa : Curcumin, prolonged aPTT and PT significantly and inhibited thrombin and FXa activities, exhibiting Anticoagulant effects .Curcumin decreased LPS-induced coagulation disturbances associated with DIC by reducing intravascular formation of fibrin deposition.

Tinospora cordifolia : Reduces the inflammation of Vascular Endothelial cells, Has Vasorelaxant action reverses the effect of Noradrenaline induced Vasoconstriction, reduces the risk of Intravascular coagulation.